Supported by CCR Office of Science and Technology Resources (OSTR)

Luminex xMAP Technology


Luminex xMAP Technology

Highly-quantitative multiplex analysis of cytokines, chemokines, growth factors, metabolites, etc. in low amount of sample.  Luminex’s xMAP® Technology combines advanced fluidics, optics, and digital signal processing with proprietary microsphere technology to deliver multiplexed assay capabilities. Featuring a flexible, open-architecture design, xMAP Technology can be configured to perform a wide variety of protein or nucleic acid assays quickly, cost-effectively, and accurately.  Application areas include cancer, immunology, cardiovascular disease, metabolic disease, inflammation, etc.

How does xMAP Technology compare with ELISA and Planar Assays?

Due to robust multiplexing, xMAP Technology potentially delivers more data in less time than other bioassay products, with comparable results to ELISA and microarray. The technology offers several other distinct advantages over traditional methods:

Speed/High Throughput

Because each microsphere serves as an individual test, a large number of different bioassays can be performed and analyzed simultaneously


A single xMAP Technology-based system can perform bioassays in several different formats, including nucleic acids and antigen-antibody binding, along with enzyme, receptor-ligand, and other protein interactions


The technology can be customized for the user’s specific needs or updated periodically by attaching a specific probe to a uniquely colored microsphere


The technology generates real-time analysis and accurate quantification of the biological interactions and high volume production of xMAP microspheres within a single lot allows assay standardization that solid-phased planar arrays cannot provide

xMAP Assays

Over 800 research xMAP assays have been developed providing a broad selection of preconfigured and custom assay panels.  All assays are performed on the MAGPIX Platform which supports xMAP assays.  Below are links to various vendors offering xMAP assays.

Bio-Plex Assay Builder

Use the Bio-Plex Assay Builder to design your customized Assay.  

MILLIPLEX® Analyte Kit Finder

Use the kit finder below to choose the correct assays for your biomarkers of interest, so you can obtain the best quality data the first time.

R&D Systems High Performance Assays

Pre-configured as well as custom assay are available.

Luminex xMAP Kit Finder

This tool is designed to provide researchers the ability to search for xMAP-based immunoassay kits from all of our Partners — in one easy step.

MAGPIX Platform

CPTR uses the MAGPIX Platform which supports xMAP assays configured on magnetic beads with up to 50-Plex analysis capabilities